Of Mouse Models and Humans

Bridging the gap with bioinformatics

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July-August 2023

Volume 111, Number 4
Page 213

DOI: 10.1511/2023.111.4.213

In a nondescript laboratory, a university researcher using mouse models to find new drugs to treat major depressive disorder finds an interesting potential drug target. She is so sure this drug target will work that she decides to go independent and seek funding to start her own company. She is given start-up funds by a Big Pharma company and she speeds up development of the drug as quickly as she can to make it ready for clinical trials. The drug passes all its trials with flying colors except for one: the final clinical trial in humans.

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