The Women Who Discovered RNA Splicing

Most scientists who played key roles in this Nobel Prize–winning breakthrough disappeared from public memory. Why does this injustice persist 40 years later?

Biology Ethics Genetics Microbiology

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September-October 2020

Volume 108, Number 5
Page 298

DOI: 10.1511/2020.108.5.298

In 1997, the Cold Spring Harbor Laboratory (CSHL) in New York celebrated the 20th anniversary of the discovery of RNA splicing. The first coauthor of the CSHL paper announcing the discovery, Louise Chow, was not invited to the celebration, even though first authorship usually implies a central role in the work.

QUICK TAKE
  • Most of the scientists who played key roles in the discovery of RNA splicing, including six women, disappeared from public memory and were overlooked for the 1993 Nobel Prize.
  • Three women were first authors on papers announcing the discovery, two of whom were scientists with their own research grants. They illustrate how women are overlooked.
  • Recognition for women, junior, or immigrant scientists cannot be achieved without thorough vetting. The Nobel committee was remiss in according all the credit to two men.
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