Building Better Growth Curves

Current standards for assessing growth in infants and children often raise unwarranted concerns. Better models could improve care.

Medicine Anatomy Physiology Statistics

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July-August 2023

Volume 111, Number 4
Page 216

DOI: 10.1511/2023.111.4.216

I first met Michael years ago, when he was just over a year old, the first and only child of a young Amish couple. He was admitted to our children’s hospital to figure out why he was growing so slowly. I was the supervising gastroenterologist that week, but he had already seen several of my colleagues, including other specialists. His diagnosis was something doctors call failure to thrive, a term plucked out of Victorian-era medicine that has no clear consensus definition and is simply what we say when a child isn’t growing as we expect.

QUICK TAKE
  • Growth curves are a standard screening tool in pediatric clinics around the world. However, those using these curves end up flagging healthy kids as having potential problems.
  • Failing to understand the patient’s context when they are not growing as expected can lead to unnecessary testing, expense, time, parental anxiety, and even risks to the patient.
  • Improving growth curves is no easy task, requiring the use of longitudinal data and more diverse datasets. Personalizing growth curves is theoretically possible with machine learning.
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