Estrogen in Men

Estradiol, the most common form of estrogen, is often called a female hormone, but men produce it too. Insight about its role comes from unusual sources.

Biology Chemistry

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November-December 2014

Volume 102, Number 6
Page 452

DOI: 10.1511/2014.111.452

In 1889, French physician Charles Édouard Brown-Séquard injected himself with an experimental mixture of testicular blood, semen, and extract from dog and guinea pig testes. After just one day, the 72-year-old doctor claimed improvement in his forearm strength, mental ability, urinary stream, and strength of fecal expulsion.

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