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Scanning the Psychedelic Brain
from the Scientist (Registration Required)
The geometric visuals and vivid imaginings experienced by those tripping on mushrooms are not, as scientists had suspected, the result of increased brain activity, according to a report out today (23 January) in Proceedings of the National Academy of Sciences. Instead, under the influence of psilocybin--the psychedelic component of magic mushrooms--brain activity and connectivity decrease. The reduced connectivity might be what frees people's minds from normal constraints, the researchers propose.
"It was often thought to be the case that these classic hallucinogens must increase brain function--you know, they expand awareness, expand consciousness--but in fact what we see is decreased activity," said Roland Griffiths of Johns Hopkins Bayview Medical Center, who was not involved in the study.
"I have to say this was totally unexpected," said David Nutt of Imperial College London, who led the study. But, he added, "when you get exactly the opposite result to what you predict, you know it is right, because there is no bias."
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