SCIENCE IN THE NEWS DAILY
Resolving Chronic Pain
from The Scientist (Registration Required)
Inflammation is correctly blamed as one of the root causes of both acute and chronic pain--and more. Not only does chronic inflammation underlie disorders such as rheumatoid arthritis, inflammatory bowel disease, and other autoimmune diseases, it has also been implicated in the pathogenesis of cancer, chronic heart failure, and neurological disorders such as Parkinson's and Alzheimer's diseases.
These conditions affect millions, and carry high health-care and socioeconomic costs. And yet, inflammation is an important physiological response that jump-starts tissue repair and more carefully tunes immune reactions. Without it, we could not fight off infection or heal from injury. Why and how does this powerful ally turn into a foe?
...While the causes of chronic pain are many and diverse, the pervasive effect it has on a patient's life--including inability to work, anxiety, depression, and even post-traumatic stress disorder--is universal.
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