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Massage's Mystery Mechanism Unmasked

from ScienceNOW

Massage's healing touch may have more to do with DNA than with good hands. A new study has revealed for the first time how kneading eases sore muscles--by turning off genes associated with inflammation and turning on genes that help muscles heal. The discovery contradicts popular claims that massage squeezes lactic acid or waste products out of tired muscles and could bring new medical credibility to the practice.

Despite massage's widespread popularity, researchers know surprisingly little about its effects on muscles. Past studies have managed to show only that a well-administered rub can reduce pain, but none has ever pinpointed how. The scant evidence makes many physicians unsure, if not outright skeptical, of the method.

Mark Tarnopolsky, a neurometabolic researcher at McMaster University in Hamilton, Canada, was one of those physicians--until he suffered a severe hamstring injury in a waterskiing accident 4 years ago. Massage therapy was part of his rehabilitation regimen, and it was so effective at easing his pain that he became determined to track down the mechanism that made him feel so good. "I thought there has to be a physiologic basis for this," he says. "And being a cellular scientist, my interest's in the cellular basis."

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