DNA Vaccines as Cancer Treatment
The content you've requested is available without charge only to active Sigma Xi members and affiliates.
If you are an active member, affiliate or individual subscriber, please log in now in order to access this article. Be sure you've entered your member or subscriber number on your profile page.
If you are not a member, affiliate or individual subscriber, you can:
Vaccines to fight foreign invaders, such as viruses and bacteria, work by presenting the immune system with a harmless version of the pathogen that the immune system learns to recognize in case a person is faced with the real pathogen. Cancerous cells are not foreign. However, they are not entirely identical with their normal counterparts, either; they carry a set of proteins slightly different from those found on normal cells, and these can be exploited to develop vaccines that stimulate an immune response against them. As the authors explain, the DNA encoding these tumor-cell proteins can be injected into cells that might help people mount a vigorous immune response against the cancers.