The content you've requested is available without charge only to active Sigma Xi members and American Scientist subscribers.
If you are an active member or an individual subscriber, please log in now in order to access this article.
If you are not a member or individual subscriber, you can:
Most everybody knows that DNA contains the blueprint for life. The names of Watson and Crick, the first scientists to figure out the structure of DNA in the 1950s, are also widely recognized. But left obscure in history is the name of the chemist who first isolated the DNA molecule itself. Johann Friedrich Miescher, working in the late 1800s, single-handedly separated out what he called "nuclein" from cells. Using arduous and complicated procedures, Miescher proved that the new substance did indeed come from cell nuclei, and that is was a fundamentally new type of organic molecule unlike anything known at the time. Although Miescher did develop some hypotheses about how "nuclein" might be involved in heredity, he ascribed to the view at the time that any one type of molecule would be too simple to account for all the variation seen within species. It would be about 75 years before the magnitude of Miescher's discovery would be fully understood.
Connect With Us:
An early peek at each new issue, with descriptions of feature articles, columns, and more. Every other issue contains links to everything in the latest issue's table of contents.News of book reviews published in American Scientist and around the web, as well as other noteworthy happenings in the world of science books.
To sign up for automatic emails of the American Scientist Update and Scientists' Nightstand issues, create an online profile, then sign up in the My AmSci area.
JSTOR, the online academic archive, contains complete back issues of American Scientist from 1913 (known then as the Sigma Xi Quarterly) through 2005.
The table of contents for each issue is freely available to all users; those with institutional access can read each complete issue.
View the full collection here.
Receive notification when new content is posted from the entire website, or choose from the customized feeds available.