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FEATURE ARTICLE

Alzheimer's Disease

The molecular origins of the disease are coming to light, suggesting several novel therapies

Vernon Ingram

Figure 6.Click to Enlarge Image

Alzheimer's disease follows the same course whether you get it at 50 or 85. By uncovering the genetics and molecular biology of Alzheimer's, scientists can now explain this observation and many other aspects of the disease at a mechanistic level. In this article, the author explains the state-of-the-art understanding of how the disease works, and shows how recent findings have helped identify new possibilities for interrupting the process. Several next-generation strategies for treating the disease are discussed, including the author's own development of decoy peptides that bind and inactivate the main Alzheimer's culprit.


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