In solving unresolved problems, we must think the unthaught, in the sense of Das ubgedachte zu denken, according to M. Heidegger. For instance, in Medicine, ALS, Amyotrophic Lateral Sclerosis early diagnosis. Notoriously, the diagnosis of Amyotrofic Lateral Sclerosis, called also "Lou Gehrig's disease", the most common form of the motor neuron diseases, is generally later due to the difficulty of recognizing its clinical early symptomatology. The earliest symptoms of ALS are typically obvious weakness and/or muscle atrophy; other presenting symptoms include muscle fasciculation, cramping, or stiffness of affected muscles; muscle weakness affecting an arm or a leg; and/or slurred and nasal speech.
Despite its till now unknown causes, as every other cerebral disorder, ALS can involve exclusively individuals with Brain Disorder Inherited Real Risk, I illustrated in former papers (1-4)
In following, it is described a precious sign, Boezio’s Sign, which plays a central role in bedside diagnosing ALS, even at birth, in its Inherited Real Risk .
In health, “intense” leg skin stimulation by mean of a pinching brings about simultaneously, due to no-local realm in biological system (5, 6), microcirculatory activation type I, associated at the level of controlateral somato-sensorial parietal cortex, followed suddenly by identical activation of omolateral motor area, detected with Quantum Biophysical Semeiotics (7-10), as well as with PET.
On the contrary, in individual involved by ALS Inherited Real Risk, and clearly by overt ASL, under experimental condition, illustrated above, brain microcirculatory activation occurs after a latency time, whose value is directly related to the seriousness of underlying disorder.
Refrences on request
posted by Sergio Stagnaro
August 5, 2012 @ 11:15 AM
JSTOR, the online academic archive, now contains complete back issues of American Scientist from its inception in 1913 (as Sigma Xi Quarterly) through 2005.
The table of contents for each issue is freely available to all users; those with institutional access can read each complete issue.
View the full collection here.
A free daily summary of the latest news in scientific research. Each story is summarized concisely and linked directly to the original source for further reading.
An early peek at each new issue, with descriptions of feature articles, columns, Science Observers and more. Every other issue contains links to everything in the latest issue's table of contents.News of book reviews published in American Scientist and around the web, as well as other noteworthy happenings in the world of science books.
To sign up for automatic emails of the American Scientist Update and Scientists' Nightstand issues, create an online profile, then sign up in the My AmSci area.