Subscribe
Subscribe
MY AMERICAN SCIENTIST
LOG IN! REGISTER!
SEARCH
 
Logo IMG

BOOK REVIEW

Molecule Talk

Mark Drapeau

The Touchstone of Life: Molecular Information, Cell Communication, and the Foundations of Life. Werner R. Loewenstein. 359 pp. Oxford University Press, 1999. $30.

The Touchstone of Life may be the most fascinating book I have read. In it, the world-renowned biophysicist Werner Loewenstein uses the concept of information to explain many of life's intimate processes. Information transfer in and between cells is Loewenstein's entire focus. According to Loewenstein, the amount of information inherent in any given arrangement of matter or energy can be computed from the number of choices we must make to arrive at a particular arrangement among all equally possible ones. The more possible arrangements there are, the more information needed to arrive at any particular arrangement. It is easy to see that by this definition a moderate-sized enzyme or a strand of DNA can contain a lot of information. Information is transmitted from molecule to molecule when the "emitter" molecule makes the atoms of the "receiver" deploy themselves in a corresponding spatial pattern via the electromagnetic force.

Using his information-exchange concept, Loewenstein clearly explains many interesting aspects of life. These include the differences between living and nonliving matter, the "handedness" of biological molecules, the time available for evolution to have occurred, the information capacity of DNA, the apparent relation between introns and organismal "simplicity," codon "wobble," control over reverse transcription of DNA, adaptive mutations and regulation of gene transcription. He even includes a brief section on Isaac Newton's alchemy research.

Occasionally, the author is quite bold. He claims that information loops—hypothetical circles drawn to represent a system in which substance A (for example, RNA) promotes the creation of substance B (protein), which in turn promotes the formation of substance A and so on—"may be in a deep sense the immanent cause of evolution." And Loewenstein implies that man is the superior being on earth, and he affirms the existence of God, both odd in a scientific book. These, however, are off-the-cuff remarks and not focal points.

Loewenstein states that this book was written with both the professional scientist and the layperson in mind, and I think both camps will enjoy it. The language throughout the book is complex like a Tennessee Williams classic yet fast-paced like a Michael Crichton thriller. Main points throughout are italicized for emphasis, making the book easier to follow. I would recommend this wide-ranging book to anyone with an interest in the world and how it got this way. People interested in evolution, cell biology and biophysics will be particularly pleased after reading The Touchstone of Life.—Mark D. Drapeau, Ecology and Evolutionary Biology, University of California, Irvine


comments powered by Disqus
 

Connect With Us:

Facebook Icon Sm Twitter Icon Google+ Icon Pinterest Icon RSS Feed

Sigma Xi/Amazon Smile (SciNight)


Latest Multimedia

Bishop with beehives

The disappearance of honeybees continues to make headlines in the news and science journals, but are their numbers still dwindling, and if so, what are the causes?

Dr. Jack Bishop, a researcher at the National Institute of Environmental Health Sciences (NIEHS) and a hobby beekeeper, discusses the external influences that are linked to bee population decline, as well as ways to help honeybees thrive.

Click the Title to view all multimedia content!


Subscribe to Free eNewsletters!

  • Sigma Xi SmartBrief:

    A free daily summary of the latest news in scientific research. Each story is summarized concisely and linked directly to the original source for further reading.

  • American Scientist Update

  • An early peek at each new issue, with descriptions of feature articles, columns, Science Observers and more. Every other issue contains links to everything in the latest issue's table of contents.

  • Scientists' Nightstand

  • News of book reviews published in American Scientist and around the web, as well as other noteworthy happenings in the world of science books.

    To sign up for automatic emails of the American Scientist Update and Scientists' Nightstand issues, create an online profile, then sign up in the My AmSci area.


EMAIL TO A FRIEND :

Of Possible Interest

Poetry On the Bookshelf: Baffle Gate

Book Review: Learning to “Fly” Biology

Book Review: Life’s Lineages

Subscribe to American Scientist